This engine is all about efficiency, the more energy you can extract from the fuel, the more power your engine has got. Increasing efficiency is ususlly done by increasing compression ratio or ignition timing advance. The limit introduces knocking, Renault is struggling with this problem.
Causes of knocking could be mixture temperature to high, caused by insufficient intercoolng or the air heating up during the transport trough the tubes. Maybe a air-water-air intercooler like Ferrari and Mercedes is just better.
Other causes would be the piston, head or valve shape. I believe they are working on it.
Still it is quite a shock, being the number two in 2014 and Ferrari copies the turbo layout and instant leap by, almost on pas with Mercedes.
If heat is the problem, i would be looking at Redbulls chassis and cooling capabilities. The have ran the Renault engine to hot in the past, with failing alternators as a result.