Additionally, it appears that the largest DNS (Direct Numberical Simulation) run ever was carried out on 4096^3 mesh points. That's 6.87x10^10 points. That required the Japanese Earth Simulator supercomputer to run it (the most powerful supercomputer in the world at the time).
http://www.cfd-online.com/Wiki/Direct_n ... tion_(DNS)
http://en.wikipedia.org/wiki/Earth_Simulator
22.4l of air at STP contains 6x10^23 molecules (Avogadro's number). So the DNS run looked at a number of mesh points equal to 2.5x10^-12 of a litre of gas.
(Note: DNS doesn't model molecules rather it solves the Navier-Stokes equations directly without using a simplified turbulence model so this comparison is purely for fun.)
We're going to need to wait a long time before we can do DNS on big things like cars...these are big numbers
We'll probably never need to carry out molecular-CFD on things like cars because the RANS/LES/DNS models will be "close enough". This is just as well as we'll probably never be able to do molecular-CFD on cars...the numbers are just stupidly huge!
If you are more fortunate than others, build a larger table not a taller fence.