I haven't seen before a car which was fast enough for pole loosing that much speed over the race.
Why does it happen?
The two variables which change are weight and longer stints.
Let's first look at stint length. Yesterday we've seen that Rosberg could lead for the length of first stint, and then it went wrong. We also seen that in Australia that they could run longer stints than many others at the first half of the race. Somehow it seems they suffer more as the race progresses -- and that happens gradually. If it's only tyre related problem, they would likely have reasonable pace after the pit-stop and then fall back. We've seen their drivers complaining about tyre deg, but then who doesn't complain?
Now weight -- looking at their qualifying pace and their results in races one may wonder whether their car is faster on fumes and just don't take full tank very well. But in such case we would likely see their relative pace improving towards the end of the race.
So what else should we look at?
I see a few things else:
1) fuel consumption
2) somehow they suffer more when running in traffic because they somehow have higher aero sensitivity?
3) maybe the performance of their suspension degrades over time?
4) they have VERY effective DRS (but this one is easy to see, we should look at the speed-trap results with and without it)?